- Any medication allergy should be reported to the healthcare provider.
- Fluids should be encouraged with antibiotic therapy.
- To obtain the most accurate culture, culture should be obtained before antibiotic therapy begins.
- The entire course of the medication should be taken to ensure eradication of the infection and decreased resistance, even if the client’s symptoms has normalized. Resistance occurs when microbes become de-sensitized to an antimicrobial.
- Multiantibiotic therapy delays development of resistance.
- When microbe is resistant to an antibiotic, antibiotic therapy must be changed. Bacteria mutate if they are in contact with antibiotics for extended periods.
- May decrease effectiveness of oral contraceptives
- Monitor for superinfections (fungal, C.difficile, vaginitis)
- Monitor for organ toxicity ( kidney and liver) (BUN and Creatinine level)
- Monitor for allergy/hypersensitivity
- High peak levels may indicate that the medication is above the toxic level.
- Medication levels must be maintained above the Minimum Effective Concentration throughout therapy to ensure that bacterial resistance does not occur.
Antimicrobial Therapy
Sensitivity and resistance:
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